Application of Effect of Pore Diameter

Pore Diameter : In general, stationary phases for IEX and HIC of proteins should have a pore diameter of 1000 Å rather than 300 Å. The 1000-Å materials afford sharper peaks because of the easier diffusion into and out of the pores. This is true even of a 21-KDa protein (ABOVE). The lower surface area and hence capacity of 1000-Å materials is usually not a problem.

Column Name : PolyPROPYL A™ Column

Compound Name : Human Growth Hormone